Vitamin B6 deficiency-
Child: 10-100 mg IM, IV to correct deficiency, then adequate diet with supplementary RDA doses to prevention recurrence.
Adult: 2.5-10 mg PO, IM, IV qd × 3 wk, then 2-5 mg qd as supplement to proper diet.
Seizures due to vitamin B6 deficiency, dependency-
Child, adult: 100 mg IM, IV in 1 dose.
Vitamin B6-responsive anemias, dependency syndrome (inborn errors of metabolism)-
Child: 100 mg IM, IV, then 2-10 mg IM or 10-100 mg PO qd.
Adult: 100-200 mg qd × 3 wk, then 2.5-100 mg qd until symptoms subside; then 50 mg qd.
Seizures from isoniazid overdose-
Child, adult: Give dose of pyridoxine equal to amount of isoniazid ingested; 1-4 gram IV then 1 gram IM q 30 min until entire dose given. |